Open AccessInhibition of p38 mitogen-activated protein kinase may decrease intestinal epithelial cell apoptosis and improve intestinal epithelial barrier function after ischemia- reperfusion injury
Author(s) -
Shaohua Zheng,
Xiaobing Fu,
Jianguo Xu,
Jingyu Zhao,
Tao Sun,
Wei Chen
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i5.656
Subject(s) - tunel assay , apoptosis , p38 mitogen activated protein kinases , mapk/erk pathway , ischemia , reperfusion injury , superior mesenteric artery , protein kinase a , endocrinology , medicine , biology , kinase , andrology , microbiology and biotechnology , biochemistry
To investigate the role of p38 mitogen-activated protein kinase in rat small intestine after ischemia-reperfusion (I/R) insult and the relationship between activation of p38 MAPK and apoptotic cell death of intestine.