Open AccessColon-specific drug delivery systems based on cyclodextrin prodrugs:In vivoevaluation of 5-aminosalicylic acid from its cyclodextrin conjugates
Author(s) -
Meijuan Zou,
Gang Cheng,
Hirokazu Okamoto,
Xiuhua Hao,
Feng An,
Fude Cui,
Kazumi Danjo
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i47.7457
Subject(s) - prodrug , pharmacology , oral administration , cecum , in vivo , chemistry , conjugate , pharmacokinetics , cyclodextrin , stomach , aminosalicylic acid , drug , drug delivery , drug carrier , small intestine , medicine , biochemistry , biology , mathematical analysis , microbiology and biotechnology , mathematics , organic chemistry
To investigate the release of cyclodextrin-5-aminosalicylic acid (CyD-5-ASA) in cecum and colon.