Open AccessExogenous acid fibroblast growth factor inhibits ischemia-reperfusion-induced damage in intestinal epithelium via regulating P53 and P21WAF-1 expression
Author(s) -
Wei Chen,
Xiaobing Fu,
Shili Ge,
Wenjuan Li,
Tong-zhu Sun,
Zhang Sheng
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i44.6981
Subject(s) - tunel assay , superior mesenteric artery , ischemia , reperfusion injury , apoptosis , immunohistochemistry , endocrinology , medicine , biology , saline , basic fibroblast growth factor , terminal deoxynucleotidyl transferase , andrology , intestinal mucosa , pathology , growth factor , biochemistry , receptor
To detect the effect of acid fibroblast growth factor (aFGF) on P53 and P21WAF-1 expression in rat intestine after ischemia-reperfusion (I-R) injury in order to explore the protective mechanisms of aFGF.