Open AccessAvidin-biotin system pretargeting radioimmunoimaging and radioimmunotherapy and its application in mouse model of human colon carcinoma
Author(s) -
Guiping Li,
Hui Zhang,
Chengfeng Zhu,
Jian Zhang,
Xufeng Jiang
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i40.6288
Subject(s) - pretargeting , radioimmunotherapy , avidin , monoclonal antibody , biodistribution , biotinylation , immunoscintigraphy , medicine , biotin , chemistry , nuclear medicine , pathology , antibody , immunology , in vitro , biochemistry
To evaluate the multi-step pretargeting radioimmunoimaging (RII) and radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma with avidin-biotin system labeled with (153)Sm.