Open AccessOverexpression of cyclooxygenase-2 in human HepG2, Bel-7402 and SMMC-7721 hepatoma cell lines and mechanism of cyclooxygenase-2 selective inhibitor celecoxib-induced cell growth inhibition and apoptosis
Author(s) -
Ningbo Liu,
Tao Peng,
Chao Pan,
Yuyu Yao,
Bo Shen,
Jing Leng
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i40.6281
Subject(s) - microbiology and biotechnology , tunel assay , apoptosis , cell growth , protein kinase b , mtt assay , celecoxib , cell culture , immunocytochemistry , chemistry , biology , blot , biochemistry , endocrinology , genetics , gene
To investigate the cyclooxygenase-2 (COX-2) expression level in human HepG2, Bel-7402 and SMMC-7721 hepatoma cell lines and the molecular mechanism of COX-2 selective inhibitor celecoxib-induced cell growth inhibition and cell apoptosis.