Potential effects of L-NAME on alcohol-induced oxidative stress | Zendy

Hafize Uzun | Zendy

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Potential effects of L-NAME on alcohol-induced oxidative stress

Author(s) -

Hafize Uzun

Publication year - 2005

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v11.i4.600

Subject(s) - malondialdehyde , oxidative stress , superoxide dismutase , chemistry , glutathione , medicine , nitric oxide synthase , catalase , nitric oxide , ethanol , biochemistry , endocrinology , enzyme

Nitric oxide (NO) is a highly reactive oxidant synthesized from L-arginine by nitric oxide synthase (NOS). NO may cause injury through the generation of potent radicals. Nw- nitro-L-arginine methyl ester (L-NAME) is a non-selective inhibitor of NOS. We aimed to evaluate whether L-NAME treatment had protective effects against oxidative stress in rats intragastrically fed with ethanol during a 4 wk-period.

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