Open AccessLow prevalence of germline hMSH6 mutations in colorectal cancer families from Spain
Author(s) -
Ana Sánchez de Abajo,
Miguel de la Hoya,
Alicia Tosar,
Javier Godino,
Juan Manuel Fernández,
Jose Lopez Asenjo,
Beatriz Pérez-Villamil,
Pedro Pérez Segura,
Eduardo Díaz-Rubio,
Trinidad Caldés
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i37.5770
Subject(s) - germline mutation , genetics , missense mutation , biology , mutation , population , nonsense mutation , germline , medicine , gene , environmental health
To investigate the prevalence and penetrance of hMSH6 mutations in Spanish HNPCC families that was negative for mutation in hMLH1 or hMSH2.