Open AccessEffects of variant UDP-glucuronosyltransferase1A1gene, glucose-6-phosphate dehydrogenase deficiency and thalassemia on cholelithiasis
Author(s) -
Yeen Huang
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i36.5710
Subject(s) - loss of heterozygosity , bilirubin , thalassemia , gene , heterozygote advantage , compound heterozygosity , biology , medicine , dehydrogenase , glucuronosyltransferase , allele , endocrinology , genetics , gastroenterology , biochemistry , enzyme , microsome
To test the hypothesis that the variant UDP-glucuronosyltransferase 1A1 (UGT1A1) gene, glucose-6-phosphate dehydrogenase (G6PD) deficiency, and thalassemia influence bilirubin metabolism and play a role in the development of cholelithiasis.