
Synergistic effect of all-trans-retinoic acid and arsenic trioxide on growth inhibition and apoptosis in human hepatoma, breast cancer, and lung cancer cellsin vitro
Author(s) -
Lemin Lin,
Baoxin Li,
Jianbing Xiao,
Danhua Lin,
Baofeng Yang
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i36.5633
Subject(s) - arsenic trioxide , glutathione , apoptosis , intracellular , viability assay , mcf 7 , mtt assay , microbiology and biotechnology , cell growth , cancer cell , cell culture , annexin , growth inhibition , retinoic acid , cancer research , cytotoxicity , chemistry , biology , cancer , biochemistry , medicine , in vitro , genetics , human breast , enzyme
To investigate the effect of all-trans-retinoic acid (ATRA) on arsenic trioxide (As(2)O(3))-induced apoptosis of human hepatoma, breast cancer, and lung cancer cells in an attempt to find a better combination therapy for solid tumors.