Open AccessStructural and functional aspects of the liver and liver sinusoidal cells in relation to colon carcinoma metastasis
Author(s) -
Katrien Vekemans,
Filip Braet
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i33.5095
Subject(s) - metastasis , medicine , mechanism (biology) , cancer research , carcinoma , pathology , cancer , philosophy , epistemology
Nowadays, liver metastasis remains difficult to cure. When tumor cells escape and arrive in the liver sinusoids, they encounter the local defense mechanism specific to the liver. The sinusoidal cells have been widely described in physiologic conditions and in relation to metastasis during the past 30 years. This paper provides an "overview" of how these cells function in health and in diseases such as liver metastasis.