Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion | Zendy

Somchai Pinlaor | Zendy; Banchob Sripa | Zendy; Ning Ma | Zendy; Yusuke Hiraku | Zendy; Puangrat Yongvanit | Zendy; Sopit Wongkham | Zendy; Chawalit Pairojkul | Zendy; Vajarabhongsa Bhudhisawasdi | Zendy; Shinji Oikawa | Zendy; Mariko Murata | Zendy; Reiji Semba | Zendy; Shosuke Kawanishi | Zendy

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Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion

Author(s) -

Somchai Pinlaor,

Banchob Sripa,

Ning Ma,

Yusuke Hiraku,

Puangrat Yongvanit,

Sopit Wongkham,

Chawalit Pairojkul,

Vajarabhongsa Bhudhisawasdi,

Shinji Oikawa,

Mariko Murata,

Reiji Semba,

Shosuke Kawanishi

Publication year - 2005

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v11.i30.4644

Subject(s) - carcinogenesis , dna damage , immunohistochemistry , cancer research , oxidative stress , pathology , nitric oxide , biology , reactive oxygen species , dna , medicine , gene , biochemistry , endocrinology

Nitrative and oxidative DNA damage such as 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) formation has been implicated in initiation and/or promotion of inflammation-mediated carcinogenesis. The aim of this study is to clarify whether these DNA lesions participate in the progression of intrahepatic cholangiocarcinoma.

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