Open AccessCorrelation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: Possible role in tumor promotion and angiogenesis
Author(s) -
Melchiorre Cervello,
Daniela Foderàa,
Ada Maria Florena,
Maurizio Soresi,
Claudio Tripodo,
Natale D’Alessandro,
Giuseppe Montalto
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i30.4638
Subject(s) - cd34 , pathology , angiogenesis , hepatocellular carcinoma , cd68 , immunohistochemistry , tryptase , tumor necrosis factor alpha , cancer research , biology , medicine , mast cell , immunology , stem cell , genetics
To investigate the association of cyclooxygenase-2 (COX-2) expression with angiogenesis and the number and type of inflammatory cells (macrophages/Kupffer cells; mast cells) within primary hepatocellular carcinoma (HCC) tissues and adjacent non-tumorous (NT) tissues.