Open AccessAntiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice
Author(s) -
Lin Jia
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i3.447
Subject(s) - gemcitabine , medicine , transplantation , carcinoma , metastasis , urology , angiogenesis , proliferating cell nuclear antigen , survival rate , pathology , immunohistochemistry , gastroenterology , chemotherapy , cancer
To investigate the anti-tumor effects of antiangiogenic therapy (a combination of TNP-470, an antiangiogenic compound, with gemcitabine, an antimetabolite) on human pancreatic carcinoma xenografts and its mechanism.