Open AccessTemporal expression of hepatic inducible nitric oxide synthase in liver cirrhosis
Author(s) -
Changli Wei,
Wei Hon,
Kang-Hoe Lee,
HoonEng Khoo
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i3.362
Subject(s) - cirrhosis , nitric oxide synthase , medicine , endocrinology , ascites , nitric oxide , hepatocyte , liver function , pathogenesis , liver function tests , biology , bilirubin , biochemistry , in vitro
Nitric oxide (NO) has been implicated in the pathogenesis of liver cirrhosis. We have found inducible nitric oxide synthase (iNOS) can be induced in hepatocytes of cirrhotic liver. This study further investigated the temporal expression and activity of hepatic iNOS in cirrhosis development.