Open AccessEffect of lipopolysaccharide on diarrhea and gastrointestinal transit in mice: Roles of nitric oxide and prostaglandin E2
Author(s) -
Yu Chih Liang,
Hung Jung Liu,
Sheng-Hsuan Chen,
Chun Chin Chen,
Liang Shung Chou,
Li Hsueh Tsai
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i3.357
Subject(s) - nitric oxide , lipopolysaccharide , nitric oxide synthase , prostaglandin e2 , prostaglandin , medicine , chemistry , cyclooxygenase , small intestine , endocrinology , intraperitoneal injection , western blot , pharmacology , biochemistry , enzyme , gene
To investigate the effect of lipopolysaccharide (LPS) on the diarrheogenic activity, gastrointestinal transit (GIT), and intestinal fluid content and the possible role of nitric oxide (NO) and prostaglandin E2 (PGE2) in gastrointestinal functions of endotoxin-treated mice.