Open AccessCirculating adhesion molecules in patients with virus-related chronic diseases of the liver
Author(s) -
Cosimo Marcello Bruno,
C Sciacca,
Danila Cilio,
Gaetano Bertino,
Anna Marchese,
Gaetana Politi,
Lucia Chinnici
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i29.4566
Subject(s) - autoanalyzer , medicine , cirrhosis , gastroenterology , intercellular adhesion molecule 1 , alanine transaminase , cell adhesion molecule , chronic liver disease , immunology , icam 1 , liver disease , inflammation
In the inflammatory state, intercellular adhesion molecule-1 (ICAM-1) and vascular cellular adhesion molecule-1 (VCAM-1) play a key role in promoting migration of immunological cells from the circulation to target site. Aim of our study was to investigate soluble forms of these molecules in patients with virus-related chronic liver diseases, to assess their behavior in different pathologies and correlation with severity of liver damage.