CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes | Zendy

Liegang Liu | Zendy

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CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes

Author(s) -

Liegang Liu

Publication year - 2005

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v11.i29.4530

Subject(s) - cyp2e1 , hepatocyte , malondialdehyde , lactate dehydrogenase , chemistry , oxidative stress , ethanol , pharmacology , western blot , biochemistry , oxidative phosphorylation , intracellular , liver injury , microbiology and biotechnology , cytochrome p450 , biology , in vitro , metabolism , enzyme , gene

To observe the relationship between ethanol-induced oxidative damage in human primary cultured hepatocytes and cytochrome P450 2E1 (CYP2E1) activity, in order to address if inhibition of CYP2E1 could attenuate ethanol-induced cellular damage.

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