Open AccessMutations outside the YMDD motif in the P protein can also cause DHBV resistant to Lamivudine
Author(s) -
Jinyang He,
Yefei Zhu,
Rui-Yi Yang,
L. Feng,
Xiuping Guo,
Fengxue Zhang,
Hongshan Chen
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i27.4261
Subject(s) - lamivudine , biology , genetics , genbank , duck hepatitis b virus , genome , gene , virology , mutation , microbiology and biotechnology , virus , hepatitis b virus , hepadnaviridae
To observe the Lamivudine resistance character of a DHBV strain in vitro and in vivo, and to analyze if the Lamivudine resistance character is caused by gene mutation or by abnormity of the Lamivudine metabolism.