Open AccessAssociation of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese
Author(s) -
Haruhisa Machida,
Kazuhiro Tsukamoto,
Chun-Yang Wen,
Yukiko Narumi,
Saburo Shikuwa,
Hajime Isomoto,
Fuminao Takeshima,
Yohei Mizuta,
Norio Niikawa,
Ikuo Murata,
Shigeru Kohno
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i27.4188
Subject(s) - genotype , single nucleotide polymorphism , odds ratio , allele , untranslated region , snp , inflammatory bowel disease , ulcerative colitis , biology , gastroenterology , restriction fragment length polymorphism , immunology , allele frequency , microbiology and biotechnology , medicine , genetics , gene , disease , rna
To examine an association between the cytotoxic T-lymphocyte antigen 4 (CTLA4) gene that plays a role in downregulation of T-cell activation and inflammatory bowel disease consisting of ulcerative colitis (UC) and Crohn's disease (CD) in the Japanese.