Open AccessMechanisms of action of leptin in preventing gastric ulcer
Author(s) -
Edward O. Adeyemi,
Salim A. Bastaki,
Irwin S. Chandranath,
Muath AlHasan,
Mohammad Fahim,
Abdu Adem
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i27.4154
Subject(s) - omeprazole , ranitidine , lansoprazole , leptin , medicine , stomach , endocrinology , mucus , antagonist , gastric acid , proton pump inhibitor , receptor antagonist , chemistry , pharmacology , receptor , biology , ecology , obesity
To investigate the effects of leptin (1-20 microg/kg) on acidified ethanol (AE)- and indomethacin (Indo)-induced gastric lesions in rats and compare it with ranitidine, lanso-prazole, and omeprazole and to determine its mechanisms of actions.