Open AccessEffects of hepatocyte growth factor/scatter factor on the invasion of colorectal cancer cellsin vitro
Author(s) -
LI Hong-wu
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i25.3877
Subject(s) - hepatocyte growth factor , colorectal cancer , in vitro , matrigel , biology , medicine , endocrinology , microbiology and biotechnology , cancer research , chemistry , andrology , cancer , receptor , biochemistry
Hepatocyte growth factor (HGF) is a multifunctional growth factor which has pleiotrophic biological effects on epithelial cells, such as proliferation, motogenesis, invasiveness and morphogenesis. There are few reports about the role of HGF played in the colorectal cancer invasion. In the present study, we tried to investigate the possible mechanism of HGF involved in the invasion of colorectal cancer cells in vitro.