Open AccessRelation of CagA seropositivity tocagPAI phenotype and histological grade of gastritis in patients withHelicobacter pyloriinfection
Author(s) -
Tadashi Shimoyama,
Shinsaku Fukuda,
Fumika Nakasato,
Teizo Yoshimura,
Tatsuya Mikami,
Akihiro Munakata
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i24.3751
Subject(s) - caga , helicobacter pylori , gastritis , virulence , biology , pathogenicity island , polymerase chain reaction , antibody , serology , immunology , antigen , microbiology and biotechnology , virology , gene , genetics
Infection with Helicobacter pylori (H pylori) possessing the cag pathogenicity island (PAI) has been associated with severe clinical outcome and CagA-antibody has been used to indicate cagPAI-positive infection. The aim of this study was to examine the accuracy of CagA seropositivity to indicate the virulence of the cagPAI in Japan.