Open AccessIntravenous acid fibroblast growth factor protects intestinal mucosal cells against ischemia-reperfusion injury via regulating Bcl-2/Bax expression
Author(s) -
Wei Chen,
Xiaobing Fu,
Shili Ge,
Tong-zhu Sun,
Gang Zhou,
Bing Han,
Yiri Du,
Haihong Li,
Zhang Sheng
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i22.3419
Subject(s) - tunel assay , superior mesenteric artery , apoptosis , reperfusion injury , ischemia , immunohistochemistry , andrology , saline , terminal deoxynucleotidyl transferase , intestinal mucosa , biology , basic fibroblast growth factor , small intestine , gene expression , endocrinology , medicine , microbiology and biotechnology , pathology , growth factor , gene , biochemistry , receptor
To detect the effect of acid fibroblast growth factor (aFGF) on apoptosis and gene expression of bax and bcl-2 gene in rat intestine after ischemia/reperfusion (I/R) injury, and to explore the protective mechanisms of aFGF.