Open AccessActivation of JAK-STAT pathway is required for platelet-derived growth factor-induced proliferation of pancreatic stellate cells
Author(s) -
Atsushi Masamune,
Masahiro Satoh,
Kazuhiro Kikuta,
Noriaki Suzuki,
Tooru Shimosegawa
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i22.3385
Subject(s) - stat3 , stat protein , platelet derived growth factor receptor , mapk/erk pathway , janus kinase , platelet derived growth factor , jak stat signaling pathway , growth factor , stat1 , hepatic stellate cell , stat , proto oncogene tyrosine protein kinase src , microbiology and biotechnology , signal transduction , chemistry , biology , cancer research , receptor , tyrosine kinase , endocrinology , biochemistry
To clarify the role of Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathway in platelet-derived growth factor (PDGF) induced proliferation in activated pancreatic stellate cells (PSCs).