Open AccessDeletion ofcagAgene ofHelicobacter pyloriby PCR products
Author(s) -
Xun Zeng,
Lihua He,
Yanling Yin,
Maojun Zhang,
Jianzhong Zhang
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i21.3255
Subject(s) - electroporation , caga , mutant , helicobacter pylori , transformation (genetics) , biology , microbiology and biotechnology , mutation , plasmid , gene , virulence , genetics
Cytotoxin-associated protein (antigen) A (CagA) plays an important role in Helicobacter pylori (H pylori) pathogenesis. Our aim was to obtain cagA- mutant strains by a new mutation method so as to better understand the mechanism of CagA in epithelial cells.