Open AccessAtorvastatin-induced severe gastric ulceration: A case report
Author(s) -
Ihab El-Hajj,
Fadi H. Mourad,
Nina S. Shabb,
Kassem Barada
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i20.3159
Subject(s) - atorvastatin , medicine , simvastatin , gastroenterology , helicobacter pylori , proton pump inhibitor , omeprazole , abdominal pain , helicobacter , drug , esomeprazole , pharmacology
A 41-year-old man presented with severe gastric ulceration 3 mo after beginning treatment with atorvastatin 20 mg once daily for hypercholesterolemia. The patient was not taking any ulcerogenic drugs and had no evidence of Helicobacter pylori infection. Proton pump inhibitor therapy was initiated and atorvastatin was replaced by simvastatin with complete resolution of gastrointestinal symptoms. To our knowledge, this is the first report of atorvastatin-induced gastric ulceration, which should be looked for in patients who develop abdominal pain while on this drug.