Open AccessExpression of fragile histidine triad in primary hepatocellular carcinoma and its relation with cell proliferation and apoptosis
Author(s) -
Nan Kang,
Zhiping Ruan,
Jing Zhao,
HongYan Qin,
Hongyan Wang,
Hui Guo,
Rui Xu
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i2.228
Subject(s) - fhit , hepatocellular carcinoma , cancer research , immunohistochemistry , apoptosis , tunel assay , metastasis , pathology , proliferating cell nuclear antigen , biology , carcinogenesis , carcinoma , medicine , tumor suppressor gene , cancer , biochemistry
To evaluate the expression of fragile histidine triad (FHIT) gene protein, product of a candidate tumor suppressor, and to investigate the relationship between FHIT, cell apoptosis and proliferation, and pathological features of primary hepatocellular carcinoma (HCC).