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Expression ofp16gene and Rb protein in gastric carcinoma and their clinicopathological significance
Author(s) -
XiuSheng He,
Ying-Hui Rong,
Qi Su,
Qing Luo,
He Dan,
YanLan Li,
Yan Chen
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i15.2218
Subject(s) - gastric mucosa , carcinoma , immunohistochemistry , polymerase chain reaction , microbiology and biotechnology , pathology , signet ring cell carcinoma , biology , gene , cancer , stomach , medicine , gastroenterology , adenocarcinoma , biochemistry
To analyze the correlation between the protein expression of p16 and Rb genes in gastric carcinoma (GC), to investigate the role of p16 gene in invasion and lymph node metastasis of GC, and to examine the deletion and mutation in exon 2 of p16 gene in GC.