Open AccessRelationships of tumor inflammatory infiltration and necrosis with microsatellite instability in colorectal cancers
Author(s) -
Jingfang Gao,
Gunnar Arbman,
Tabasum Imran Wadhra,
Hong Zhang,
XiaoFeng Sun
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i14.2179
Subject(s) - microsatellite instability , colorectal cancer , medicine , infiltration (hvac) , univariate analysis , pathology , necrosis , multivariate analysis , survival analysis , oncology , gastroenterology , cancer , microsatellite , biology , allele , biochemistry , physics , gene , thermodynamics
The relationships between microsatellite instability (MSI) and survival in colorectal cancer patients are not consistent. The favorable survival of patient with MSI has been suggested to be related to pronounced inflammatory infiltration; however, the reason for non-association of MSI with survival is unclear. Our aims were to investigate the associations of inflammatory infiltration and tumor necrosis (TN) with microsatellite status and clinicopathological factors in colorectal cancer patients in whom MSI was not related to survival.