Open AccessHeat shock protein 70 antisense oligonucleotide inhibits cell growth and induces apoptosis in human gastric cancer cell line SGC-7901
Author(s) -
Zhenjuan Zhao,
Wei Shen
Publication year - 2005
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v11.i1.73
Subject(s) - propidium iodide , microbiology and biotechnology , apoptosis , flow cytometry , cell cycle , hsp70 , dna fragmentation , biology , heat shock protein , cancer cell , cell culture , cell growth , oligonucleotide , cell , programmed cell death , chemistry , cancer , dna , biochemistry , gene , genetics
Heat shock protein (HSP)70 is over-expressed in human gastric cancer and plays an important role in the progression of this cancer. We investigated the effects of antisense HSP70 oligomer on human gastric cancer cell line SGC-7901, and its potential role in gene therapy for this cancer.