Eradication ofHelicobacter pylorisignificantly reduced gastric damage in nonsteroidal anti-inflammatory drug-treated Mongolian gerbils | Zendy

Chun-Chao Chang | Zendy; Sheng-Hsuan Chen | Zendy; Gi Shih Lien | Zendy; Horng Yuan Lou | Zendy; Ching Ruey Hsieh | Zendy; Chia-Lang Fang | Zendy; Shiann Pan | Zendy

Open Access

Eradication ofHelicobacter pylorisignificantly reduced gastric damage in nonsteroidal anti-inflammatory drug-treated Mongolian gerbils

Author(s) -

Chun-Chao Chang,

Sheng-Hsuan Chen,

Gi Shih Lien,

Horng Yuan Lou,

Ching Ruey Hsieh,

Chia-Lang Fang,

Shiann Pan

Publication year - 2005

Publication title -

world journal of gastroenterology

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v11.i1.104

Subject(s) - rofecoxib , medicine , gastroenterology , helicobacter pylori , stomach , gastritis , myeloperoxidase , prostaglandin , gerbil , cyclooxygenase , inflammation , chemistry , enzyme , biochemistry , ischemia

To examine the effect of eradication of Helicobacter pylori prior to usage of NSAIDs, by investigating gastric inflammatory activity, myeloperoxidase (MPO) activity, prostaglandin (PG) E2 synthesis in H pylori-infected, and H pylori-eradicated gerbils followed by administration of indomethacin and rofecoxib.

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