Open AccessCorrelation of expression of multidrug resistance protein and messenger RNA with99mTc-methoxyisobutyl isonitrile (MIBI) imaging in patients with hepatocellular carcinoma
Author(s) -
Hai Wang,
Xiaoping Chen,
Fa-Zu Qiu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i9.1281
Subject(s) - p glycoprotein , hepatocellular carcinoma , messenger rna , multiple drug resistance , immunohistochemistry , efflux , liver cancer , medicine , washout , spect imaging , carcinoma , gene expression , cancer , cancer research , pathology , chemistry , nuclear medicine , biology , drug resistance , gene , biochemistry , microbiology and biotechnology
To explore whether P-glycoprotein (Pgp) and other pumps, multidrug resistance-associated protein (MRP) and lung resistance protein (LRP), could affect tumor accumulation and efflux of 99mTc-MIBI in liver cancer.