Open AccessEstablishment of mice model with human viral hepatitis B
Author(s) -
Lifen Gao,
Wei Sun,
Chao Ma,
Suxia Liu,
Xiaoyan Wang,
Lining Zhang,
Ying-Lin Cao,
Faliang Zhu,
Yu-Gang Liu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i6.841
Subject(s) - microbiology and biotechnology , hepatitis b virus , hbsag , recombinant dna , virology , biology , transfection , ctl* , spleen , orthohepadnavirus , cell culture , immune system , virus , immunology , gene , cd8 , biochemistry , genetics
To establish a mice model of hepatitis B by using HBV-transgenic mice, and to transfer HBV-specific cytotoxic T lymphocytes (CTL) induced from syngeneic BALB/c mice immunized by a eukaryotic expression vector containing HBV complete genome DNA.