Open AccessEffects of PI3K and p42/p44 MAPK on overexpression of vascular endothelial growth factor in hepatocellular carcinoma
Author(s) -
Gengwen Huang,
Lian-Yue Yang,
Wencheng Lu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i6.809
Subject(s) - vascular endothelial growth factor , mapk/erk pathway , ly294002 , epidermal growth factor , microbiology and biotechnology , phosphatidylinositol , chemistry , kinase , biology , pi3k/akt/mtor pathway , signal transduction , cancer research , cell culture , vegf receptors , genetics
To study the relationship between hypoxia or epidermal growth factor (EGF) and the overexpression of vascular endothelial growth factor (VEGF) in hepatocellular carcinoma (HCC) and the signal transduction pathway of the transcription of VEGF in hepatoma cells.