Open AccessCoexpression of cholecystokinin-B/gastrin receptor and gastrin gene in human gastric tissues and gastric cancer cell line
Author(s) -
Jianjiang Zhou,
Manling Chen,
Qun-Zhou Zhang,
JianKun Hu,
Wenling Wang
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i6.791
Subject(s) - cancer , gastrin , medicine , cholecystokinin b receptor , gastritis , gastric mucosa , biology , malignancy , pathology , cholecystokinin , receptor , cancer research , stomach , gastroenterology , endocrinology , secretion
To compare the expression patterns of cholecystokinin-B (CCK-B)/gastrin receptor genes in matched human gastric carcinoma and adjacent non-neoplastic mucosa of patients with gastric cancer, inflammatory gastric mucosa from patients with gastritis, normal stomachs from 2 autopsied patients and a gastric carcinoma cell line (SGC-7901), and to explore their relationship with progression to malignancy of human gastric carcinomas.