Open Access
Downregulation of retinoic acid receptor-β2expression is linked to aberrant methylation in esophageal squamous cell carcinoma cell lines
Author(s) -
Zhongmin Liu,
Fang Ding,
Mingzhou Guo,
Liyong Zhang,
Min Wu,
Zhihua Liu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i6.771
Subject(s) - methylation , dna methylation , cancer research , retinoic acid receptor beta , downregulation and upregulation , biology , retinoic acid receptor , retinoic acid , gene silencing , bisulfite sequencing , cell culture , microbiology and biotechnology , medicine , gene expression , gene , genetics
To study the role of hypermethylation in the loss of retinoic acid receptor beta(2) (RARbeta(2)) in esophageal squamous cell carcinoma (ESCC).