Open AccessEffect ofin vitrointerferon-beta administration on hepatitis C virus in peripheral blood mononuclear cells as a predictive marker of clinical response to interferon treatment for chronic hepatitis C
Author(s) -
Kaori Mochizuki,
Tatehiro Kagawa,
Shinji Takashimizu,
Kazuya Kawazoe,
Seiichiro Kojima,
Naruhiko Nagata,
Atsushi Nakano,
Yasuhiro Nishizaki,
Koji Shiraishi,
Masaru Itakura,
Norihito Watanabe,
Tetsuya Mine,
Shinya Matsuzaki
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i5.733
Subject(s) - peripheral blood mononuclear cell , medicine , hepatitis c virus , interferon , immunology , hepatitis c , in vitro , interferon alfa , rna , alpha interferon , virus , virology , gastroenterology , biology , biochemistry , gene
To test whether in vitro incubation of peripheral blood mononuclear cells (PBMC) with interferon (IFN) could efficiently decrease hepatitis C virus-RNA (HCV-RNA) amount and to analyze whether this effect was associated with clinical response to IFN.