Open AccessProtective effect of taurine on hypochlorous acid toxicity to nuclear nucleoside triphosphatase in isolated nuclei from rat liver
Author(s) -
Juxiang Li,
Yilin Pang,
Chaoshu Tang,
Zaiquan Li
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i5.694
Subject(s) - taurine , chemistry , glutathione , hypochlorous acid , biochemistry , gtp' , nucleoside triphosphate , enzyme , nucleotide , amino acid , gene
Taurine has been shown to be an effective scavenger of hypochlorous acid (HOCl). The role of HOCl is well established in tissue damage associated with inflammation and injury. In the present study, the effect of HOCl on nuclear nucleoside triphosphatase of hepatocytes and the ability of taurine to prevent this effect were investigated.