Open AccessInhibitor RNA blocks the protein translation mediated by hepatitis C virus internal ribosome entry sitein vivo
Author(s) -
Xuesong Liang,
Jianqi Lian,
Yonggang Zhou,
Mo-Bin Wan
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i5.664
Subject(s) - internal ribosome entry site , replicon , transfection , microbiology and biotechnology , luciferase , reporter gene , biology , virology , untranslated region , gene expression , hepatitis c virus , lipofectamine , ribosome , translation (biology) , gene , rna , messenger rna , virus , plasmid , vector (molecular biology) , recombinant dna , genetics
To investigate the inhibitory effect of hepatitis C virus internal ribosome entry site (HCV IRES) specific inhibitor RNA (IRNA) on gene expression mediated by HCV IRES in vivo.