Helicobacterspecies sequences in liver samples from patients with and without hepatocellular carcinoma | Zendy

Rinaldo Pellicano | Zendy

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Helicobacterspecies sequences in liver samples from patients with and without hepatocellular carcinoma

Author(s) -

Rinaldo Pellicano

Publication year - 2004

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v10.i4.598

Subject(s) - hepatocellular carcinoma , cirrhosis , helicobacter pylori , helicobacter , gastroenterology , hepatitis c virus , medicine , liver cancer , colorectal cancer , metastasis , cancer , pathology , virus , virology

Only a minority of patients carrying a defined viral aetiologic agent develop cirrhosis and ultimately hepatocellular carcinoma (HCC), the mechanism underlying the worsening is still undefined. Experimental infection by Helicobacter hepaticus in mice causes chronic hepatitis and HCC and recently, more Helicobacter species (Helicobacter spp.) have been detected in the liver of patients suffering from cholestatic diseases and HCC arising from non-cirrhotic liver. We investigated whether Helicobacter spp. sequences could be detected in the liver of patients with cirrhosis and HCC compared to subjects with metastasis to liver from colon cancer.

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