Open AccessExpression of nuclear factor-kappa B and target genes in gastric precancerous lesions and adenocarcinoma: Association withHelicobactor pyloricagA (+) infection
Author(s) -
Guifang Yang,
Changsheng Deng,
Yan Xiong,
Ling Gong,
Bi-Cheng Wang,
Jun Luo
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i4.491
Subject(s) - caga , helicobacter pylori , intestinal metaplasia , rapid urease test , medicine , dysplasia , adenocarcinoma , gastritis , biopsy , gastroenterology , pathology , biology , cancer , gene , biochemistry , virulence
To examine the expression of nuclear factor kappaB (NF-kappaB) and its target genes in intestinal metaplasia (IM), dysplasia (DYS) and gastric carcinoma (GC) infected with Helicobacter pylori (H pylori) and to investigate the mechanism underlying H pylori cytotoxin associated gene A (cag A) infection leading to gastric adenocarcinoma.