Open AccessHerpes simplex virus thymidine kinase and ganciclovir suicide gene therapy for human pancreatic cancer
Author(s) -
Jing Wang,
Xiaoxuan Lu,
Daozhen Chen,
Shufeng Li,
Lishan Zhang
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i3.400
Subject(s) - suicide gene , ganciclovir , thymidine kinase , herpes simplex virus , genetic enhancement , pancreatic cancer , cancer research , bystander effect , virology , biology , virus , cancer , human cytomegalovirus , immunology , gene , genetics
To investigate the in vitro effects of suicide gene therapy system of herpes simplex virus thymidine kinase gene (HSV-TK) in combination with the treatment of nucleotide analog-ganciclovir (GCV) on human pancreatic cancer, and to provide a novel clinical therapeutic method for human pancreatic cancer.