Herpes simplex virus thymidine kinase and ganciclovir suicide gene therapy for human pancreatic cancer | Zendy

Jing Wang | Zendy; Xiaoxuan Lu | Zendy; Daozhen Chen | Zendy; Shufeng Li | Zendy; Lishan Zhang | Zendy

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Herpes simplex virus thymidine kinase and ganciclovir suicide gene therapy for human pancreatic cancer

Author(s) -

Jing Wang,

Xiaoxuan Lu,

Daozhen Chen,

Shufeng Li,

Lishan Zhang

Publication year - 2004

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v10.i3.400

Subject(s) - suicide gene , ganciclovir , thymidine kinase , herpes simplex virus , genetic enhancement , pancreatic cancer , cancer research , bystander effect , virology , biology , virus , cancer , human cytomegalovirus , immunology , gene , genetics

To investigate the in vitro effects of suicide gene therapy system of herpes simplex virus thymidine kinase gene (HSV-TK) in combination with the treatment of nucleotide analog-ganciclovir (GCV) on human pancreatic cancer, and to provide a novel clinical therapeutic method for human pancreatic cancer.

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