Open AccessAntiangiogenic effect of somatostatin receptor subtype 2 on pancreatic cancer cell line: Inhibition of vascular endothelial growth factor and matrix metalloproteinase-2 expressionin vitro
Author(s) -
Manoj Kumar,
Zheng-Ren Liu,
Laxmi Thapa,
Qing Chang,
Da-Yu Wang,
Renyi Qin
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i3.393
Subject(s) - somatostatin receptor 2 , vascular endothelial growth factor , lipofectamine , transfection , microbiology and biotechnology , immunohistochemistry , pancreatic cancer , cell culture , somatostatin , medicine , biology , endocrinology , somatostatin receptor , cancer research , cancer , gene , vegf receptors , recombinant dna , vector (molecular biology) , biochemistry , genetics
To investigate the anti-angiogenic effect of somatostatin receptor subtype 2 (SSTR2) gene transfer into pancreatic cancer cell line PC-3, and the mechanisms involved in this effect.