Open AccessHemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma
Author(s) -
Xiao Wu,
Weiwen Liu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i3.376
Subject(s) - loss of heterozygosity , biology , transversion , dna methylation , cpg site , epigenetics , carcinogenesis , microbiology and biotechnology , methylation , hccs , gene , genetics , tumor suppressor gene , gene mutation , single strand conformation polymorphism , cancer research , allele , exon , mutation , gene expression
To analyze the genetic and epigenetic alterations of RUNX3 gene, a potential putative tumor suppressor gene, in hepatocellular carcinoma (HCC).