Open AccessEffects of phosphorothioate anti-sense oligodeoxynucleotides on colorectal cancer cell growth and telomerase activity
Author(s) -
Xishan Wang,
Kuan Wang,
Li Xue,
Songbin Fu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i23.3455
Subject(s) - telomerase , microbiology and biotechnology , apoptosis , flow cytometry , cell growth , sense (electronics) , biology , growth inhibition , oligonucleotide , telomerase reverse transcriptase , cell culture , colorectal cancer , in vitro , chemistry , cancer , biochemistry , dna , gene , genetics
To investigate the inhibitory effect of phosphorothioate anti-sense oligodeoxynucleotides (PASODN) on colorectal cancer LS-174T cells in vitro and the mechanism of inhibition of telomerase activity in these cells.