Open AccessDown-modulation of heat shock protein 70 and up-modulation of Caspase-3 during schisandrin B-induced apoptosis in human hepatoma SMMC-7721 cells
Author(s) -
Yi-Feng Wu,
Ming-Fu Cao,
Yanping Gao,
Fei Chen,
Tao Wang,
Edward Zumbika,
Kaixian Qian
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i20.2944
Subject(s) - apoptosis , caspase , microbiology and biotechnology , hsp70 , western blot , biology , cell culture , heat shock protein , programmed cell death , cell growth , mtt assay , chemistry , biochemistry , genetics , gene
To investigate the effect of schisandrin B (Sch B) on proliferation and apoptosis of human hepatoma SMMC-7721 cells in vitro and regulation of Hsp70 and Caspases-3, 7, 9 expression by Sch B.