Open AccessEstablishment of transgenic mice carrying gene encoding human zinc finger protein 191
Author(s) -
Jianzhong Li,
Xia Chen,
Hua Yang,
Shuiliang Wang,
Xuelian Gong,
Hao Feng,
Binhui Guo,
Lingjia Yu,
Zhugang Wang,
Jian Fu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i2.264
Subject(s) - transgene , genetically modified mouse , biology , gene , zinc finger , microbiology and biotechnology , gene expression , western blot , genetics , transcription factor
Human zinc finger protein 191 (ZNF191) was cloned and characterized as a Kruppel-like transcription factor, which might be relevant to many diseases such as liver cancer, neuropsychiatric and cardiovascular diseases. Although progress has been made recently, the biological function of ZNF191 remains largely unidentified. The aim of this study was to establish a ZNF 191 transgenic mouse model, which would promote the functional study of ZNF191.