Open AccessGenetic detection of Chinese hereditary nonpolyposis colorectal cancer
Author(s) -
Long Cui,
Heiying Jin,
Hui-Yu Cheng,
Yu-di Yan,
Ronggui Meng,
Dehong Yu
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i2.209
Subject(s) - germline mutation , single strand conformation polymorphism , dna mismatch repair , genetics , biology , dna sequencing , exon , gene , genomic dna , mutation , colorectal cancer , dna repair , cancer
To explore the germline mutations of the two main DNA mismatch repair genes (hMSH2 and hMLH1) between patients with hereditary non-polyposis colorectal cancer (HNPCC) and suspected (atypical) HNPCC.
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