Open AccessA candidate DNA vaccine elicits HCV specific humoral and cellular immune responses
Author(s) -
Lizhi Zhu,
Jing Liu,
Ye Ye,
Yao Xie,
YuYing Kong,
Guangdi Li,
Yuan Wang
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i17.2488
Subject(s) - adjuvant , antigen , immunogenicity , immune system , biology , splenocyte , virology , antibody , immunology , dna vaccination , antibody titer , titer , immunization
To investigate the immunogenicity of candidate DNA vaccine against hepatitis C virus (HCV) delivered by two plasmids expressing HCV envelope protein 1 (E1) and envelope protein 2 (E2) antigens respectively and to study the effect of CpG adjuvant on this candidate vaccine.