Open AccessLack of evidence for leukocyte maternal microchimerism in primary biliary cirrhosis
Author(s) -
Kenichi Nomura,
Yoshio Sumida,
Takaharu Yoh,
Atsuhiro Morita,
Yosuke Matsumoto,
Sawako Taji,
Naohisa Yoshida,
Masahito Minami,
Yoshito Itoh,
Shigeo Horiike,
Keisuke Kataoka,
Masafumi Taniwaki,
Takeshi Okanoue
Publication year - 2004
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v10.i16.2415
Subject(s) - microchimerism , primary biliary cirrhosis , immunology , fetus , pathogenesis , chimera (genetics) , medicine , biopsy , pregnancy , biology , pathology , gene , genetics
It is reasonable to assume that microchimerism could also be involved in the induction of primary biliary cirrhosis (PBC). However, previous reports investigated only fetus-microchimerism in women patients. Maternal microchimerism has not been investigated until now. The current study aimed to clear either maternal microchimerism was involved in the pathogenesis of PBC or not.